Genome sequencing of pancreatic cancer: differential expression by location
نویسندگان
چکیده
The results demonstrated that pancreatic ductal carcinoma (PDAC) of the body/tail was associated with more transcriptional and genomic changes, correlated worse prognosis, than PDAC head. different mutation types gene expression tumour locations provide deep insight into carcinogenesis or metastasis PDAC, suggest early diagnostic therapeutic strategies. SNV, single-nucleotide variations; NLS, Nuclear localization sequence; MB, million base-pairs; UTR, untranslated region.
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ژورنال
عنوان ژورنال: British Journal of Surgery
سال: 2021
ISSN: ['1365-2168', '0007-1323']
DOI: https://doi.org/10.1093/bjs/znaa063